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Research
Intracranial infection, one of the complications of traumatic brain injury, is usually associated with inflammation. Several microRNAs (miRNAs), including miR-155, have been reported to be critical modulators ...
Journal of Inflammation 2017 14:17
Published on: 9 August 2017
Review
Interleukin (IL)-35 is a relatively newly discovered member of IL-12 cytokine family that is unique in that it is a dimer formed by two subunits. The review documents the structure, secretion and signal transd...
Journal of Inflammation 2017 14:16
Published on: 7 August 2017
Commentary
Wnt5A is a chemokine secreted by inflammatory-activated human macrophages that sustains their inflammatory response in an autocrine manner. High levels of Wnt5A are found in sera of patients with sepsis and se...
Journal of Inflammation 2017 14:15
Published on: 13 July 2017
Research
Indeed, intracerebral hemorrhage (ICH) account for only 15% of all strokes but it is one of the most devastating subtype of stroke associated with behavioral, cognitive and neurological deficits. The primary c...
Journal of Inflammation 2017 14:14
Published on: 9 June 2017
Research
Traumatic brain injury (TBI) is a public health issue. As the major complaint in 51% of TBI patients, chronic pain is an important aspect in TBI treatment. Tetramethylpyrazine (TMP) is an important compound in Li...
Journal of Inflammation 2017 14:13
Published on: 8 June 2017
Review
The presence of cytosolic double-stranded DNA molecules can trigger multiple innate immune signalling pathways which converge on the activation of an ER-resident innate immune adaptor named “STimulator of INte...
Journal of Inflammation 2017 14:11
Published on: 7 June 2017
Research
The red cell distribution width (RDW) is a widely available, inexpensive, and highly reproducible test that reflects the range of the red cell sizes. Any process that releases reticulocytes in the circulation ...
Journal of Inflammation 2017 14:12
Published on: 7 June 2017
Short report
Wnt5A is released by activated macrophages and elevated levels have been detected in sepsis patients with severe systemic inflammation. However, the signalling and functional effects of Wnt5A in the vascular e...
Journal of Inflammation 2017 14:10
Published on: 19 May 2017
Short Report
Obesity-induced inflammation causes skeletal muscle atrophy accompanied by disruption of oxidative metabolism and is implicated in metabolic complications such as insulin resistance and type 2 diabetes. We pre...
Journal of Inflammation 2017 14:9
Published on: 11 May 2017
Research
Adipocyte fatty acid-binding protein, also known as aP2 or fatty acid-binding protein 4 (FABP4), plays an important role in inflammatory and metabolic responses in adipocytes and macrophages. Recent work has d...
Journal of Inflammation 2017 14:8
Published on: 20 March 2017
Research
Ulinastatin or urinary trypsin inhibitor (UTI) has been shown to ameliorate the inflammatory response induced by experimental severe acute pancreatitis (SAP) and hence reduce the mortality, however the mechani...
Journal of Inflammation 2017 14:7
Published on: 20 March 2017
Research
The dysfunction of articular chondrocytes is a crucial step in rheumatoid arthritis (RA) pathogenesis while its molecular mechanisms are not fully known. This study was aimed to investigate the expression of a...
Journal of Inflammation 2017 14:6
Published on: 1 March 2017
Research
An altered amniotic cytokine profile has been reported in inflammatory pregnancy complications with a leading role for IL-6, a marker of the foetal systemic inflammatory response. Up to this date there is no e...
Journal of Inflammation 2017 14:5
Published on: 15 February 2017
Short report
Peritoneal macrophages are widely used in immunological studies. The cells can be collected under non-elicited (resident) or elicited (e.g., with Brewer thioglycollate broth injection) conditions, and their ph...
Journal of Inflammation 2017 14:4
Published on: 10 February 2017
Research
Statins (HMG CoA reductase inhibitors), in addition to reducing circulating cholesterol and incidence of coronary heart disease, also have pleiotropic, anti-inflammatory effects. Patients with chronic liver di...
Journal of Inflammation 2017 14:3
Published on: 2 February 2017
Research
Airway viral infections cause the exacerbations of asthma and chronic obstructive pulmonary disease. PD-L1, also known as B7-H1, is an immune-checkpoint molecule that plays a role in an escape mechanism of vir...
Journal of Inflammation 2017 14:2
Published on: 17 January 2017
Research
It is well considered that reactive oxygen species (ROS) plays a prominent causative role in the development of allergic rhinitis (AR), and eosinophils cells as important allergic inflammatory cells contribute...
Journal of Inflammation 2017 14:1
Published on: 13 January 2017
Research
The C825T polymorphism (rs5443) of the Guanine Nucleotide-Binding protein subunit β3 (GNB3) gene has been associated with obesity, essential hypertension, atherosclerosis, coronary diseases, and cerebrovascular e...
Journal of Inflammation 2016 13:39
Published on: 9 December 2016
Research
The innate immune Toll-like receptors (TLRs) 2/4 are important players in chronic low-grade inflammation called metabolic inflammation in obesity and type-2 diabetes (T2D). While TLR2/4 expression changes asso...
Journal of Inflammation 2016 13:38
Published on: 8 December 2016
Review
Ethyl pyruvate (EP) is a simple derivative of pyruvic acid, which is an important endogenous metabolite that can scavenge reactive oxygen species (ROS). Treatment with EP is able to ameliorate systemic inflamm...
Journal of Inflammation 2016 13:37
Published on: 3 December 2016
Research
Macrophages serve as intracellular reservoirs of S. aureus. Recent in vitro studies have confirmed high level resistance by S. aureus to macrophage mediated killing and the intracellular persistence of Staphyloco...
Journal of Inflammation 2016 13:36
Published on: 28 November 2016
Review
Prostate is an immune-competent organ normally populated by inflammatory cells. Prostatic inflammation origin can be multi-factorial and there are some emerging evidences on its possible role as a factor invol...
Journal of Inflammation 2016 13:35
Published on: 25 November 2016
Research
Metformin has been used for the treatment of type 2 diabetes by suppressing hepatic gluconeogenesis. It has been shown that the subclinical inflammatory responses play important roles in the pathogenesis of ty...
Journal of Inflammation 2016 13:34
Published on: 24 November 2016
Research
Neuroinflammation (NI) is a key feature in the pathogenesis and progression of infectious and non-infectious neuropathologies, and its amelioration usually improves the patient outcome. Peripheral inflammation...
Journal of Inflammation 2016 13:33
Published on: 29 October 2016
Research
Chemokine ligands (CCLs) play a pivotal role in tissue injury before and after kidney transplantation. Meanwhile, transplantation improves patient’s survival and diminishes morbidity. It is hypothesized, then,...
Journal of Inflammation 2016 13:32
Published on: 26 October 2016
