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  1. Neutrophils are a heterogeneous population capable of antimicrobial functions associated with pre-activation/activation and tissue regeneration. The specific polarisation of immune cells is mediated by the mod...

    Authors: Paweł Piatek, Magdalena Namiecinska, Natalia Lewkowicz, Małgorzata Kulińska-Michalska, Zbigniew Jabłonowski, Mariola Matysiak, Sylwia Michlewska, Marek Wieczorek and Przemysław Lewkowicz
    Citation: Journal of Inflammation 2024 21:16
  2. PM exposure can induce inflammatory and oxidative responses; however, differences in these adverse effects have been reported depending on the chemical composition and size. Moreover, inflammatory mechanisms s...

    Authors: Damariz Marín-Palma, Jorge H. Tabares-Guevara, Natalia Taborda, Maria T. Rugeles and Juan C. Hernandez
    Citation: Journal of Inflammation 2024 21:15
  3. The DNA-dependent protein kinase (DNA-PK) complex comprises a catalytic (PRKDC) and two requisite DNA-binding (Ku70/Ku80) subunits. The role of the complex in repairing double-stranded DNA breaks (DSBs) is est...

    Authors: Mohamed A. Ghonim, Jihang Ju, Kusma Pyakurel, Salome V. Ibba, Mai M. Abouzeid, Hamada F. Rady, Shigemi Matsuyama, Luis Del Valle and A. Hamid Boulares
    Citation: Journal of Inflammation 2024 21:14
  4. Exposure to noxious particles, including cigarette smoke and fine particulate matter (PM2.5), is a risk factor for chronic obstructive pulmonary disease (COPD) and promotes inflammation and cell death in the lung...

    Authors: Chiwook Chung, Suk Young Park, Jin-Young Huh, Na Hyun Kim, ChangHo Shon, Eun Yi Oh, Young-Jun Park, Seon-Jin Lee, Hwan-Cheol Kim and Sei Won Lee
    Citation: Journal of Inflammation 2024 21:13
  5. Interplay between systemic inflammation and programmed cell death contributes to the pathogenesis of acute lung injury (ALI). cAMP-regulated transcriptional coactivator 1 (CRTC1) has been involved in the norma...

    Authors: Meng Chen, Jian Lv, Ningning Guo, Tuo Ji, Yu Fang, Zhihua Wang and Xianghu He
    Citation: Journal of Inflammation 2024 21:12
  6. Asthma is a prevalent respiratory inflammatory disease. Abnormal apoptosis of bronchial epithelial cells is one of the major factors in the progression of asthma. Peripheral benzodiazepine receptors are highly...

    Authors: Yurui Liu, Zhengze Zhang, Yuewen He, Ruogen Li, Yuhao Zhang, Hao Liu, Yong Wang and Wuhua Ma
    Citation: Journal of Inflammation 2024 21:11
  7. Beyond their crucial role in hemostasis, platelets possess the ability to regulate inflammation and combat infections through various mechanisms. Stringent control of macrophage activation is essential during ...

    Authors: Shuhua Luo, Riping Xu, Pengyun Xie, Xiaolei Liu, Chunxiu Ling, Yusha Liu, Xuedi Zhang, Zhengyuan Xia, Zhanghui Chen and Jing Tang
    Citation: Journal of Inflammation 2024 21:10
  8. Environmental tobacco smoke (ETS) is known to cause lung inflammatory and injurious responses. Smoke exposure is associated with the pathobiology related to lung fibrosis, whereas the mechanism that ETS exposu...

    Authors: Qixin Wang, Chiara Goracci, Isaac Kirubakaran Sundar and Irfan Rahman
    Citation: Journal of Inflammation 2024 21:9
  9. Sepsis is a dysregulated systemic inflammatory response triggered by infection, resulting in organ dysfunction. A major challenge in clinical pediatrics is to identify sepsis early and then quickly intervene t...

    Authors: Sean Leonard, Hailey Guertin, Natalya Odoardi, Michael R. Miller, Maitray A. Patel, Mark Daley, Gediminas Cepinskas and Douglas D. Fraser
    Citation: Journal of Inflammation 2024 21:7
  10. Lactobacillus casei possesses many kinds of bioactivities, such as anti-inflammation and anti-oxidant, and has been applied to treating multiple inflammatory diseases. However, its role in mastitis prevention has...

    Authors: Ke Li, Ming Yang, Mengyue Tian, Li Jia, Yinghao Wu, Jinliang Du, Lining Yuan, Lianmin Li and Yuzhong Ma
    Citation: Journal of Inflammation 2024 21:5
  11. Tissue-plasminogen activator (tPA) is a serine protease well known for its fibrinolytic function. Recent studies indicate that tPA could also modulate inflammation via plasmin generation and/or by receptor mediat...

    Authors: Célia Seillier, Léonie Lesec, Pauline Hélie, Charlotte Marie, Denis Vivien, Fabian Docagne, Brigitte Le Mauff and Olivier Toutirais
    Citation: Journal of Inflammation 2024 21:4
  12. 4R is a tobacco cembranoid that binds to and modulates cholinergic receptors and exhibits neuroprotective and anti-inflammatory activity. Given the established function of the cholinergic system in pain and in...

    Authors: Luis G. Rivera-García, Adela M. Francis-Malavé, Zachary W. Castillo, Calvin D. Uong, Torri D. Wilson, P. A. Ferchmin, Vesna Eterovic, Michael D. Burton and Yarimar Carrasquillo
    Citation: Journal of Inflammation 2024 21:2
  13. Mitochondrial diseases (MDs) are genetic disorders characterized by dysfunctions in mitochondria. Clinical data suggest that additional factors, beyond genetics, contribute to the onset and progression of this...

    Authors: Kevin Aguilar, Carla Canal, Gemma Comes, Sandra Díaz-Clavero, Maria Angeles Llanos, Albert Quintana, Elisenda Sanz and Juan Hidalgo
    Citation: Journal of Inflammation 2024 21:1
  14. Coronavirus disease 2019 (COVID-19) induces a dysfunctional immune response, inflammation, autoantibody production, and coagulopathy, which are symptoms that bear resemblance to those of autoimmune diseases, i...

    Authors: Ha Yeon Jeong, Jin-Sil Park, Jin Seok Woo, Kun Hee Lee, Jeong Won Choi, Hye Yeon Kang, Hyun Sik Na, Yeon Su Lee, In Gyu Um, Sung-Hwan Park and Mi-La Cho
    Citation: Journal of Inflammation 2023 20:46
  15. This article has been retracted. Please see the Retraction Notice for more detail:

    Authors: Chih-Zen Chang, Shu-Chuan Wu, Chih-Lung Lin and Aij-Lie Kwan
    Citation: Journal of Inflammation 2023 20:45
  16. Lonicera japonica Thunb (LJT) is a commonly used herbal soup to treat inflammation-related diseases. However, the effect of LJT on ALI is unknown. The present study was aimed at investigating the protective ef...

    Authors: Qinyao Jia, Jing wen, Qi Yang, Shengming Liu, Jianwu Zhang, Tao Wang and Yao Cheng
    Citation: Journal of Inflammation 2023 20:44
  17. The heme oxygenase-1 (HO-1) enzyme pathway is of crucial importance in the removal of toxic blood components and regulation of neuroinflammation following hemorrhagic stroke. Although a circadian pattern depen...

    Authors: Luise Henrich, Iva Kiessling, Matti Steimer, Sibylle Frase, Sandra Kaiser and Nils Schallner
    Citation: Journal of Inflammation 2023 20:43
  18. Smoking, alcohol abuse, and hypertension are – among others, potential risk factors for cardiovascular diseases. These risk factors generate oxidative stress and cause oxidative stress-induced DNA damage, resu...

    Authors: Huakang Zhou, Dilaware Khan, Sajid Muhammad Hussain, Norbert Gerdes, Carsten Hagenbeck, Majeed Rana, Jan Frederick Cornelius and Sajjad Muhammad
    Citation: Journal of Inflammation 2023 20:41
  19. The recent pandemic outbursts, due to SARS-CoV-2, have highlighted once more the central role of the inflammatory process in the propagation of viral infection. The main consequence of COVID-19 is the inductio...

    Authors: Bianca Vezzani, Mariasole Perrone, Marianna Carinci, Laura Palumbo, Alberto Tombolato, Denis Tombolato, Claudio Daminato, Valentina Gentili, Roberta Rizzo, Gianluca Campo, Luca Morandi, Alberto Papi, Savino Spadaro, Paolo Casolari, Marco Contoli, Paolo Pinton…
    Citation: Journal of Inflammation 2023 20:40
  20. Clinical cases and experimental evidence revealed that electronic cigarettes (ECIG) induce serious adverse health effects, but underlying mechanisms remain to be fully uncovered. Based on recent exploratory ev...

    Authors: Mizanur Rahman, Shanzina Iasmin Sompa, Micol Introna, Swapna Upadhyay, Koustav Ganguly and Lena Palmberg
    Citation: Journal of Inflammation 2023 20:39
  21. Hendra virus is an emerging virus with a geographically broad host reservoir. In humans, Hendra virus causes excessive inflammatory disease of the lung and nervous system. Our current understanding as to how H...

    Authors: Kristian Barry, Christopher Harpur, Maggie Lam, Michelle D. Tate and Ashley Mansell
    Citation: Journal of Inflammation 2023 20:38
  22. Fermented butyrate exhibits an anti-inflammatory response to maintain immune homeostasis within the gut. However, the effect and underlying mechanism of butyrate on myasthenia gravis (MG) remain unclear. The c...

    Authors: Jing Sun, Juanjuan Chen, Qinfang Xie, Mengjiao Sun, Wenjing Zhang, Hongxia Wang, Ning Liu, Qi Wang and Manxia Wang
    Citation: Journal of Inflammation 2023 20:37
  23. Soluble Epoxide Hydrolase (sEH) metabolizes anti-inflammatory epoxyeicosatrienoic acids and critically affects airway inflammation in chronic obstructive pulmonary disease (COPD). Considering the excessive end...

    Authors: Yue Yu, Ailin Yang, Xin He, Bo Wu, Yanjun Wu, Yunxiao Li, Shan Nie, Bo Xu, Haoyan Wang and Ganggang Yu
    Citation: Journal of Inflammation 2023 20:36
  24. Diabetes mellitus is one of the causes of poor ventricular remodelling and poor cardiac recovery after myocardial infarction (MI). We previously reported that tissue factor pathway inhibitor-2 (TFPI2) was down...

    Authors: Mengqi Guo, Zongyi Xia, Yefeng Hong, Hongwei Ji, Fuhai Li, Wenheng Liu, Shaohua Li, Hui Xin, Kai Tan and Zhexun Lian
    Citation: Journal of Inflammation 2023 20:35
  25. Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are life threatening pulmonary diseases, and we are now lack of effective therapeutic methods. Inflammatory response...

    Authors: Chunguang Yan, Jing Chen, Huifang Tang, Chunmin Deng, Qi Zhang and Ximo Wang
    Citation: Journal of Inflammation 2023 20:34
  26. When exposed to various microenvironmental stimuli, macrophages are highly plastic and primarily polarized into the pro-inflammatory M1-type and the anti-inflammatory M2-type, both of which perform almost enti...

    Authors: Tingting Xia, Shengping Fu, Ruilin Yang, Kang Yang, Wei Lei, Ying Yang, Qian Zhang, Yujie Zhao, Jiang Yu, Limei Yu and Tao Zhang
    Citation: Journal of Inflammation 2023 20:33
  27. Cardiometabolic diseases are associated with low-grade inflammation early in life and persists into old age. The long latency period presents opportunities for early detection, lifestyle modification and inter...

    Authors: Erik Fung, Eunice Y. S. Chan, Kwan Hung Ng, Ka Man Yu, Huijun Li and Yulan Wang
    Citation: Journal of Inflammation 2023 20:32
  28. An increasing body of evidence now shows that the long-term mortality of patients with sepsis are associated with various sepsis-related immune cell defects. Alternative splicing (AS), as a sepsis-related immu...

    Authors: Dilixiati Tuerdimaimaiti, Buzukela Abuduaini, Shaotao Kang, Jinliang Jiao, Mengchen Li, Wolazihan Madeniyati, Baihetinisha Tuerdi, Gulisitan Aili, Reyila Tuerhong and Ajiguli Kulaxi
    Citation: Journal of Inflammation 2023 20:31
  29. To avoid the overuse of antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), acting via cyclooxygenase (COX) inhibition, have been used to reduce pain and as an alternative treatment for uncomplicated ...

    Authors: Soumitra Mohanty, Ciska Lindelauf, John Kerr White, Andrea Scheffschick, Ewa Ehrenborg, Isak Demirel, Hanna Brauner and Annelie Brauner
    Citation: Journal of Inflammation 2023 20:30
  30. The strong perioperative stress response caused by surgical anesthesia can significantly suppress immune function, and the body is in a state of immunosuppression for 3 to 4 days after surgery, which leads to ...

    Authors: Yinzhou Zhang, Junying Wei, Xinyuan Wu, Mengting Jiang, Wuhua Ma and Yuhui Li
    Citation: Journal of Inflammation 2023 20:29
  31. Ferroptosis in alveolar and bronchial epithelial cells is one of the main mechanisms underlying the development of chronic obstructive pulmonary disease (COPD). Sodium pyruvate (NaPyr) is a natural antioxidant...

    Authors: Ziwen Zhao, Zhao Xu, Jingwen Chang, Liwei He, Zijin Zhang, Xiaoyu Song, Xianbang Hou, Fangtian Fan and Zhijun Jiang
    Citation: Journal of Inflammation 2023 20:28
  32. According to the World Health Organization (WHO), air pollution is one of the most serious threats for our planet. Despite a growing public awareness of the harmful effects of air pollution on human health, th...

    Authors: Adrianna Gałuszka-Bulaga, Karolina Tkacz, Kazimierz Węglarczyk, Maciej Siedlar and Jarek Baran
    Citation: Journal of Inflammation 2023 20:26
  33. Infectious preterm birth (PTB) is one of the most important causes of perinatal death. It is difficult to find reliable biomarkers accurate to gestational weeks for infectious PTB prediction clinically. Infect...

    Authors: Jiayi Li, Jianrong Ge, Na Ran, Changwu Zheng, Yumeng Fang, Danna Fang, Qian Yang and Yeling Ma
    Citation: Journal of Inflammation 2023 20:25
  34. Acute liver failure (ALF) is one of the most common life-threatening diseases in adults without previous liver disease. Glycogen synthase kinase 3β (GSK3β) is a serine/threonine protein kinase that is widely d...

    Authors: Danmei Zhang, Chunxia Shi, Qingqi Zhang, Yukun Wang, Jin Guo and Zuojiong Gong
    Citation: Journal of Inflammation 2023 20:24
  35. To compare the severity of radiation-induced lung injury (RILI) after the right lung of SD rats received interstitial brachytherapy and stereotactic radiotherapy (SBRT).

    Authors: Zhuo Chen, Bin Wang, Zhouxue Wu, Hua Xiao, Yang Yang, Junying Fan, Yingjiang Gu, Chuan Chen and Jingbo Wu
    Citation: Journal of Inflammation 2023 20:23
  36. Astrocytes respond to injury and disease through a process known as reactive astrogliosis, of which inflammatory signaling is one subset. This inflammatory response is heterogeneous with respect to the inducti...

    Authors: Caroline Lindblad, Susanne Neumann, Sólrún Kolbeinsdóttir, Vasilios Zachariadis, Eric P. Thelin, Martin Enge, Sebastian Thams, Lou Brundin and Mikael Svensson
    Citation: Journal of Inflammation 2023 20:22
  37. Uncontrolled inflammation contributes to the progression of organ damage in acute conditions, such as acetaminophen-induced acute liver injury (APAP-ALI) and there are limited treatments for this condition. AT...

    Authors: Jennifer A. Cartwright, Joanna P. Simpson, Natalie Z. M. Homer and Adriano G. Rossi
    Citation: Journal of Inflammation 2023 20:20

    The Correction to this article has been published in Journal of Inflammation 2023 20:27

  38. Neuropathic pain (NP) is a widespread chronic pain with a prevalence of 6.9–10% in the general population, severely affecting patients’ physical and mental health. Accumulating evidence indicated that the immu...

    Authors: Xiangsheng Zhang, Jiurong Cheng, Yingdong Deng, Caiyun Guo, Yu Cao, Suo Wang, Chenxi Zhou, Ziqiang Lin, Simin Tang and Jun Zhou
    Citation: Journal of Inflammation 2023 20:19
  39. To perform a systematic literature review and meta-analysis on endothelial cell (EC) markers that are involved and dysregulated in systemic lupus erythematosus (SLE) in relation to disease activity, as EC dysr...

    Authors: S. C. Bergkamp, M. J. Wahadat, A. Salah, T. W. Kuijpers, V. Smith, S. W. Tas, J. M. van den Berg, S. Kamphuis and D. Schonenberg-Meinema
    Citation: Journal of Inflammation 2023 20:18
  40. Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, which can cause heart failure, arrhythmia and even sudden death. It is the major cause of disability and deat...

    Authors: Yawen Wu, Shilin Wei, Xiangyang Wu, Yongnan Li and Xue Han
    Citation: Journal of Inflammation 2023 20:17
  41. Delayed neutrophil apoptosis during sepsis may impact neutrophil organ accumulation and tissue immune homeostasis. Elucidating the mechanisms underlying neutrophil apoptosis may help identify potential therape...

    Authors: Yinjiaozhi Li, Ruoming Tan, Ranran Li, Rui Tian, Zhaojun Liu, Xiaoli Wang, Erzhen Chen, Tingting Pan and Hongping Qu
    Citation: Journal of Inflammation 2023 20:16
  42. The Kynurenine Pathway (KP) of tryptophan degradation and glutamate toxicity is implicated in several neurological disorders, including depression. The therapeutic potential of mesenchymal stromal cells (MSC),...

    Authors: Fyyaz Siddiqui, Denis Gallagher, Hannah Shuster-Hyman, Lianet Lopez, Andrée Gauthier-Fisher and Clifford L Librach
    Citation: Journal of Inflammation 2023 20:15
  43. Osteoarthritis (OA) is a common joint disease and is the main cause of physical disability in the elderly. Currently, there is no adequate therapeutic strategy to reverse the progression of OA. Many natural pl...

    Authors: Qing Ding, Ruizhuo Zhang, Gaohong Sheng, Tianqi Wang, Shaoze Jing, Tian Ma, Shanxi Wang, Hongqi Zhao, Hua Wu and Wenkai Li
    Citation: Journal of Inflammation 2023 20:14
  44. Acute lung injury (ALI) is a life-threatening condition that fundamentally results from inflammation and edema in the lung. There are no effective treatments available for clinical use. Previously, we found th...

    Authors: Yeomyeong Kim, Cho-Rong Bae, Dongyeop Kim, Hyejeong Kim, Sunghye Lee, Haiying Zhang, Minyoung Noh, Young-Myeong Kim, Naoki Mochizuki and Young-Guen Kwon
    Citation: Journal of Inflammation 2023 20:13

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