Skip to content


Featured review: Pathogenesis of eosinophilic chronic rhinosinusitis

Eosinophilic chronic rhinosinusitis (ECRS) is an intractable and persistent disease of the nose and paranasal sinuses. Eosinophilic degradation and accumulation, the release of cytokines and chemokines, and mucus production have an important role in the pathogenesis of this disease.

This review describes the clinical course, diagnosis, and treatment of ECRS as well as its pathophysiology and the role of eosinophils, mucus, cytokines, and other mediators in the pathogenesis of ECRS.


Most accessed articles RSS

View all articles

Aims and scope

Journal of Inflammation is an open access, peer-reviewed online journal publishing articles on all aspects of research into inflammation. Non-research articles are specially commissioned by the Editors-in-Chief. 

Read more

Submit your review

Journal of Inflammation welcomes review articles on a variety of different topics relating to the scope of the journal. Submit your review today.

For further queries or to discuss the limited funds which may be available to cover the article-processing charge, please contact the editorial team.

Editor profiles

Prof Paul Kirkham, Editor-in-Chief

Prof Kirkham is Professor of Cell Biology at the University of Wolverhampton and a fellow of the HEA. His research interests focus on understanding the mechanisms of disease pathogenesis driven by oxidative stress and its impact on cell function and inflammation, particularly in relation to respiratory disease.

Prof Adriano Rossi, Editor-in-Chief

Prof Rossi holds the position of Personal Chair in Respiratory and Inflammation Pharmacology at the University of Edinburgh. Prof Rossi is a Fellow of the Society of Biology and a Fellow of the British Pharmacological Society. His research involves investigating the cellular processes and signalling mechanisms controlling inflammation with a focus on understanding inflammation resolution.


Affiliated with the British Inflammation Research Association (BIRAs).

2017 Journal Metrics