Table 2 Selected studies measuring serum CRP before and after CPAP
Study | Study design | Study population characteristics | OSA definition | Minimum CPAP usage | Outcome |
|---|---|---|---|---|---|
Carniero et al. 2009 [63] | Case–control | 7 severely obese men | AHI > 30 | ≥ 5 h/day for 3 months | No significant change |
Chung et al. 2011 [64] | Case–control | 25 total: 22 men, 3 women | AHI ≥15 | ≥ 4 h/day for 3 months | No significant change |
Colish et al. 2012 [65] | Case–control | 47 total: 32 men, 15 women; 25 obese, 22 overweight | AHI ≥ 15 | ≥ 4.5 h/day for 12 months | No significant change |
Dorkova et al. 2008 [66] | Case–control | 16 total: 15 men, 1 woman | AHI ≥ 30 | ≥ 4 h/day for 8 weeks | No significant change |
Harsch et al. 2004 [67] | Case–control | 20 obese patients | AHI = 48.6 ± 9.1 (mean ± SD) | 5.32 ± 0.67 h/day (mean ± SD) for 8 weeks | No significant change |
Iesato et al. 2007 [68] | Case–control | 36 total | AHI ≥ 20 | ≥ 4 h/day for 3 months | Significantly decreased |
Ishida et al. 2009 [69] | Case–control | 40 total: 32 men, 8 women | AHI > 20 | > 4 h/day, 5d/week for 6 months | Significantly decreased |
Patruno et al. 2007 [58] (APAP) | Case–control | 15 total | AHI > 20 | > 4 h/day for 3 months | Significantly decreased |
Patruno et al. 2007 [58] (CPAP) | Case–control | 16 total | AHI > 20 | > 4 h/day for 3 months | Significantly decreased |
Ryan et al. 2007 [70] | Case–control | 49 total | AHI > 15 | > 4 h/day for 6 weeks | No significant change |
Schiza et al. 2010 [61] | Case–control | 436 total: 252 men, 184 women | AHI > 15 | > 4 h/day, 5d/week for 12 months | Significantly decreased |
Steiropoulos et al. 2007 [71] | Case–control | 20 total: 16 men, 4 women | AHI > 15 | ≥ 4 h/night for 6 months | Significantly decreased |
Yokoe et al. 2003 [18] | Case–control | 17 total | AHI ≥ 20 | 1 month | Significantly decreased |
Zhao et al. 2011 [72] | Case–control | 27 total | AHI ≥ 30 | Good compliance for 3 months | Significantly decreased |