Table 4 ROC analyses of biomarker combinations on PICU day-1 sepsis
Biomarker Combinations | AUC | 95% CIs | P-value |
|---|---|---|---|
IL-8, IL-6 | 1.000 | 1.000–1.000 | < 0.001 |
MCP-1, HSP70 | 1.000 | 1.000–1.000 | < 0.001 |
MCP-1, IL-6 | 1.000 | 1.000–1.000 | < 0.001 |
HSP70, Hyaluronan | 1.000 | 1.000–1.000 | < 0.001 |
Hyaluronan, IL-6 | 1.000 | 1.000–1.000 | < 0.001 |
HSP70, IL-6 | 0.998 | 0.989–1.000 | < 0.001 |
M-CSF, IL-6 | 0.995 | 0.982–1.000 | < 0.001 |
IL-8, HSP70 | 0.978 | 0.942–1.000 | < 0.001 |
HSP70, M-CSF | 0.975 | 0.937–1.000 | < 0.001 |
IL-8, Hyaluronan | 0.965 | 0.913–1.000 | < 0.001 |
MCP-1, Hyaluronan | 0.965 | 0.897–1.000 | < 0.001 |
Hyaluronan, M-CSF | 0.965 | 0.913–1.000 | < 0.001 |
IL-8, MCP-1 | 0.962 | 0.890–1.000 | < 0.001 |
MCP-1, M-CSF | 0.962 | 0.890–1.000 | < 0.001 |
IL-8, M-CSF | 0.953 | 0.877–1.000 | < 0.001 |