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Table 3 Receiver operating curve analyses for predicting PICU day-1 sepsis

From: Pediatric sepsis inflammatory blood biomarkers that correlate with clinical variables and severity of illness scores

Biomarker

AUC

95% CI

P-value

IL-6

0.995

0.982–1.000

< 0.001

HSP70

0.975

0.937– 1.000

< 0.001

MMP3

0.968

0.923–1.000

< 0.001

MCP-1

0.967

0.904–1.000

< 0.001

Hyaluronan

0.965

0.913–1.000

< 0.001

M-CSF

0.943

0.853–1.000

< 0.001

IL-1RA

0.939

0.870–1.000

< 0.001

MMP10

0.927

0.851–1.000

< 0.001

IL-8

0.923

0.837–1.000

< 0.001

G-CSF

0.882

0.775–0.990

< 0.001

MIP-1β

0.880

0.765–0.995

< 0.001

MMP8

0.879

0.757–1.000

< 0.001

MMP1

0.874

0.751–0.996

< 0.001

IL-10

0.868

0.757–0.978

< 0.001

Elastase 2

0.867

0.733–1.000

< 0.001

IL-18

0.855

0.736–0.974

< 0.001

TNFα

0.852

0.729–0.976

< 0.001

NGAL

0.845

0.713–0.977

< 0.001

Resistin

0.842

0.686–0.999

< 0.001

RANTES

0.833

0.695–0.970

< 0.001

MMP7

0.825

0.675–0.975

< 0.001

MIG

0.775

0.623–0.927

0.003

MMP9

0.747

0.572–0.923

0.007

MMP2

0.735

0.572–0.898

0.011

  1. AUC, area-under-the-curve; CI, confidence interval