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Fig. 5 | Journal of Inflammation

Fig. 5

From: Lonicera japonica Thunb extract ameliorates lipopolysaccharide-induced acute lung injury associated with luteolin-mediated suppression of NF-κB signaling pathway

Fig. 5

Lut decreased edema, neutrophils, and inflammation in LPS-treated mice. Note:Summarized data representing the effects of different concentrations of Lut on (A) the survival overcomes, (B) W/D ratio, (C) total protein and (D) neutrophils in BALF. (E) The changes of histological structure of the mouse lung in different groups (20×). (F) The mRNA expression levels of Bax and Bcl-2 was tested using qRT-PCR. (G) The protein expression levels of Bax and Bcl-2 was tested using western blot assay. The expression levels of of (H), IL-1β (I) IL-6 and (J) TNF-α in mice. (K) The mRNA expression levels of IL-1β, IL-6, IL-10 and TNF-α in the tissues of mice were tested by qRT-PCR; (L) The protein expression levels of IL-1β, IL-6, IL-10 and TNF-α in the tissues of mice were tested by western blot assays. Bar = 50 μm. ###p < 0.001 vs. control group; *p < 0.05, **p < 0.01 and ***p < 0.001 vs. ALI model group

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Journal of Inflammation

ISSN: 1476-9255

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