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Fig. 6 | Journal of Inflammation

Fig. 6

From: Interleukin-6-elicited chronic neuroinflammation may decrease survival but is not sufficient to drive disease progression in a mouse model of Leigh syndrome

Fig. 6

Microgliosis, but not astrogliosis, is decreased in a region-dependent manner in GFAP-IL6 mice due to NDUFS4 deficiency at the mid stage. a Quantification of IBA-1 fluorescence intensity in the VN, cerebellum, OB, cortex, and CA1, as well as the number of IBA-1+ cells in the cortex, and CA1 of the different genotypes. b GFAP mean fluorescence intensity quantification in the VN, cerebellum, OB, cortex, and CA1. Ndufs4 effect p ≤ 0.05, GF-IL6 effect p ≤ 0.05, ♦ p ≤ 0.05 interaction between both factors

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