Fig. 2From: Interleukin-6-elicited chronic neuroinflammation may decrease survival but is not sufficient to drive disease progression in a mouse model of Leigh syndromeAstrocyte-tagged IL-6 overexpression barely affects the motor or respiratory phenotype of Ndufs4 KO mice. a Latency to fall in the accelerating rotarod. b Total distance travelled in the OF test. c Day of onset of clasping behavior in Ndufs4 KO and GFAP-IL6/Ndufs4 KO mice. d Tidal volume and (e) respiratory frequency at the different stages. In d and e “n” values are indicated above the X axis. ● Ndufs4 effect p≤ 0.05, ★ GF-IL6 effect p≤ 0.05, ♦ p≤ 0.05 interaction between both factors, *p = 0.05–0.01Back to article page