Fig. 4

Effects of Cinna-Sol® on IL-1β release in an in vivo lung-inflammatory model. a Schematic representation of the experimental design. The C57BL/6 J-WT mice were divided into two groups: a control group receiving PBS treatment (CTRL), and a group subjected to intranasal LPS-induced lung inflammation. Within the LPS group, there were three sub-groups: PBS inhalation (LPS), CINNA inhalation (CINNA + LPS), and DEXA inhalation (DEXA + LPS) received as aerosol pre-treatments. Following lung extraction, the release of IL-1β from samples was analyzed by ELISA assay. b Bar graph showing ELISA results of IL-1β levels released by lungs of C57BL/6 J mice in control condition (CTRL) (n = 15), after LPS treatment (LPS) (n = 17) or pre-treated with aerosol inhalation of CINNA (CINNA + LPS) (n = 5) or DEXA (DEXA + LPS) (n = 4). ** = p < 0,01, *** = p < 0,001