Sodium butyrate alleviates R97-116 peptide-induced myasthenia gravis in mice by improving the gut microbiota and modulating immune response

Table 1 Significant differentially abundant phyla, genera, and species between MG patients and healthy controls (HCs)

	Items	P value	Mean abundance of HCs	Mean abundance of MG patients	Enrichment
Phyla	Bacteroidetes	0.0356	77.8074	68.8298	MG < HC
Phyla	Proteobacteria	0.0271	1.6230	4.6873	HC < MG
Genera	Butyricimonas	0.0407	0.1470	0.1432	MG < HC
	Eggerthella	0.0099	0.0035	0.0210	HC < MG
	Parasutterella	0.0271	0.3348	0.7212	HC < MG
	Gordonibacter	0.0406	0.0010	0.0096	HC < MG
	Gemella	0.0444	0.0012	0.0106	HC < MG
	Turicimonas	0.0449	0.0295	0.0518	HC < MG
	Enterococcus	0.0492	0.0021	0.0201	HC < MG
Species	Prevotella copri	0.0331	24.9951	10.6873	MG < HC
	Alistipes putredinis	0.0333	2.2294	1.3336	MG < HC
	Blautia wexlerae	0.0208	0.1290	0.0563	MG < HC
	Blautia obeum	0.0383	0.0954	0.0345	MG < HC
	Butyricimonas synergistica	0.0422	0.0558	0.0112	MG < HC
	Parabacteroides goldsteinii	0.0429	0.0441	0.0001	MG < HC
	Alistipes indistinctus	0.0432	0.0310	0.0085	MG < HC
	Streptococcus oralis	0.0054	0.0002	0.0043	HC < MG
	Streptococcus gordonii	0.0093	0.0001	0.0071	HC < MG
	Streptococcus mitis	0.0262	0.0021	0.0169	HC < MG
	Streptococcus anginosus	0.0325	0.0033	0.0137	HC < MG
	Streptococcus parasanguinis	0.0399	0.0225	0.0563	HC < MG
	Eggerthella lenta	0.0099	0.0035	0.0210	HC < MG
	Parasutterella excrementihominis	0.0271	0.3348	0.7212	HC < MG
	Streptococcus anginosus group	0.0325	0.0033	0.0137	HC < MG
	Lactobacillus sanfranciscensis	0.0339	0.0003	0.0243	HC < MG
	Gordonibacter pamelaeae	0.0406	0.0010	0.0096	HC < MG
	Turicimonas muris	0.0449	0.0295	0.0518	HC < MG

ISSN: 1476-9255