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Fig. 5 | Journal of Inflammation

Fig. 5

From: Sodium butyrate alleviates R97-116 peptide-induced myasthenia gravis in mice by improving the gut microbiota and modulating immune response

Fig. 5

Transcriptomic sequencing and analysis of total B cells in spleen from mice in EAMG and NaB-treated group. A Volcano plot of differentially expressed genes (DEGs), in which 1218 DEGs were up-regulated while 3359 DEGs were down-regulated. GO enrichment at the biological process (BP), cellular component (CC), and molecular function (MF) for the up-regulated DEGs (B) and down-regulated DEGs (C) (The horizontal axis is the name of GO item). Filtered KEGG pathways related to MG or autoimmune diseases which annotated by the up-regulated DEGs (D) and down-regulated DEGs (E). (The bubble color changes from green-brown-red, the smaller the enrichment p Value, the greater the significance)

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