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Fig. 5 | Journal of Inflammation

Fig. 5

From: SARS-CoV-2 spike protein accelerates systemic sclerosis by increasing inflammatory cytokines, Th17 cells, and fibrosis

Fig. 5

Upregulation of inflammatory cytokines in BLM-induced SSc mice following injection of pcDNA3.1-SARS2-Spike and pLEX307-ACE2-puro (n = 5). (a) Immunohistochemical analysis of IL-6, IL-4, IL-17, TNFα, and IL-1β in skin and lung tissues isolated from sacrificed SSc mouse models at 5 weeks post-injection. (b) Graph illustrating the area positive for IL-6, IL-4, IL-17, TNFα, and IL-1β in skin and lung tissues

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Journal of Inflammation

ISSN: 1476-9255

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