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Fig. 3 | Journal of Inflammation

Fig. 3

From: SARS-CoV-2 spike protein accelerates systemic sclerosis by increasing inflammatory cytokines, Th17 cells, and fibrosis

Fig. 3

Accelerated fibrosis in BLM-induced SSc mice following injection of pcDNA3.1-SARS2-Spike and pLEX307-ACE2-puro (n = 5). (a) Confocal microscopy analysis showing CD4 (FITC), IL-17 (PE), and IL-4 (APC) staining. (b) Graph depicting the number of IL-4 + cells and IL-17 + cells among CD4 + positive cells. (c) Flow cytometric analysis illustrating the percentage of ex vivo Th2 and Th17 cells from the skin or lung in BLM-induced SSc mice

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Journal of Inflammation

ISSN: 1476-9255

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