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Fig. 3 | Journal of Inflammation

Fig. 3

From: The TFPI2–PPARγ axis induces M2 polarization and inhibits fibroblast activation to promote recovery from post-myocardial infarction in diabetic mice

Fig. 3

Effects of TFPI2 knockdown on macrophage polarization in post-MI myocardium

(a) Western blot analysis of iNOS, Arg-1 and PPARγ at 3 weeks after infarction (n = 3). (b) Co-immunofluorescence staining of the macrophage marker (CD68, green) and M1 macrophage marker (CD86, red) of infarcted myocardium samples (n = 3). (c) Co-immunofluorescence staining of the macrophage marker (CD68, green) and M2 macrophage marker (CD206, red) of infarcted myocardium samples (n = 3). Sham, sham operation; MI, myocardial infarction; sh-TFPI2, sh-TFPI2 transfection; sh-NC, sh-NC transfection. Data represent mean ± standard deviation (SD). Data were analyzed using one-way ANOVA and Tukey’s post hoc test. *P < 0.05, **P < 0.01, ***P < 0.001

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Journal of Inflammation

ISSN: 1476-9255

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