Fig. 2

Dynamic alternative splicing was identified in apoptosis-related genes among different groups. A The distribution of the junction reads from SHISA5 in samples are visualized for the different groups. The numbers of SJ reads are included as labels with the splice junctions. Altered exons are marked using red boxes. B The upper panel shows a slicing events model. The lower panel shows a boxplot indicating the splicing ratio profile across the splicing events from SHISA5 from the 79 samples shown in (A). C Visualization of the distribution of junction reads for IFI27 in samples from the various study groups. The splice junctions are labelled with the number of SJ reads. Altered exons are shown in the red box. D The upper panel shows a splicing events model. The boxplot shown in the lower panel indicates the splicing ratio profile across the splicing events from IFI27 from the 79 samples, as seen in (C). The validation of IF127 and SHISHA5 is shown in (E–F)