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Fig. 1 | Journal of Inflammation

Fig. 1

From: Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis

Fig. 1

NaPyr reduces CSE-induced cell death in A549 and BEAS-2B cells. (A)Effect of NaPyr on cell proliferation of A549. (n = 6) (B) Changes of viablity in A549 after CSE stimulation. (n = 6; **p < 0.01 vs. Control) (C) Changes of viablity in A549 after CSE stimulation and the intervention of NaPyr. (n = 6; ##P < 0.01 vs. Control; **p < 0.01 vs. CSE) (D)Effect of NaPyr on cell proliferation of BEAS-2B. (n = 6) (E) Changes of viablity in BEAS-2B after CSE stimulation. (n = 6; *P < 0.05; **p < 0.01 vs. Control) (F) Changes of viablity in BEAS-2B after CSE stimulation and the intervention of NaPyr. (n = 6; ##P < 0.01 vs. Control;**p < 0.01 vs. CSE) (G) Cytotoxicity of Erastin to BEAS-2B. (n = 6; *P < 0.05;**p < 0.01 vs. Control) (H) Changes of viablity in A549 after Erastin stimulation and the intervention of NaPyr. (n = 6; ##P < 0.01 vs. Control; *P < 0.05,**p < 0.01 vs. CSE) (I) Changes of viablity in BEAS-2B after Erastin stimulation and the intervention of NaPyr. (n = 6; ##P < 0.01 vs. Control; *P < 0.05,**p < 0.01 vs. CSE)

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Journal of Inflammation

ISSN: 1476-9255

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