Fig. 1

Overview of studies dissecting stroke-related gene expression differences in the brain. (A) (left) Excluded and included stroke studies from NCBI GEO. (Right) Exclusion of datasets subdivided by species (mouse, rat, human and primates) with missing information, duplicates, pooled samples, poor quality controls, and no clear separation between stroked and non-stroked groups were further excluded. (B) Distribution of individual studies by time point, stroke model and sex. (C) Number of gene hits in individual studies. More information about the IDs can be found in Suppl Table 1. (D) Principal component analysis (PCA) of all stroke studies across different species and time points