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Table 2 Inter-batch precision (%CV) and accuracy (%NOM) assessment for APAP and AT7519 standards analysed in 3 batches, over two days

From: Analysis of AT7519 as a pro-resolution compound in an acetaminophen-induced mouse model of acute inflammation by UPLC-MS/MS

nominal concentration (ng/mL)

N

APAP

AT7519

mean calculated concentration (ng/mL)

%CV

%NOM

mean calculated concentration (ng/mL)

%CV

%NOM

0.5

3

0.53

3.1

105.60

0.54

5.86

108.53

1

3

0.86

13.51

85.70

0.97

3.32

96.60

2.5

3

2.68

12.11

107.39

2.36

4.84

94.21

5

3

5.05

2.29

101.02

4.84

3.70

96.83

10

3

9.93

3.16

99.33

9.50

4.86

94.96

25

3

24.33

3.03

97.30

25.33

4.16

101.30

45

3

45.11

1.84

100.25

46.14

3.00

102.54

50

3

51.70

2.50

103.40

52.48

3.82

104.96