Fig. 4

Dio ameliorates IL-1β-induced cartilage matrix degradation. Chondrocytes were exposed to IL-1β (10 ng/mL) with or without Dio (200, 400, and 800 ng/mL) for 24 h. A Representative western blots and (B) quantitative analysis of collagen II and aggrecan in each group. C Collagen II and (D) aggrecan were observed by immunofluorescence after the cells treated with IL-1β (10 ng/mL) in absence or presence of Dio (800 ng/mL). ^#P < 0.05 vs. control group; ^*P < 0.05 vs. IL-1β group;.^**P < 0.01 vs. IL-1β group; n = 3