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Fig. 1 | Journal of Inflammation

Fig. 1

From: Network analyses reveal new insights into the effect of multicomponent Tr14 compared to single-component diclofenac in an acute inflammation model

Fig. 1

A Heat map highlighting expression profile (Log2 FC) of the unique DEGs in Tr14 and diclofenac treatments compared to their respective control at various time points in the AIR Molecular Interaction Map. B Venn diagram showing unique DEGs present in the AIR submaps, which are directly involved in regulating acute inflammatory processes/phenotypes. Only the top 5 genes based on the highest absolute log2FC value are labeled in each group (Tr14, diclofenac, and shared DEGs with opposing expression profiles in both treatment groups). C Immune cell profiling using the aggregated log twofold change expression profile of marker genes in Tr14 vs. saline control and diclofenac vs. placebo control. The red color indicates an increase, whereas the blue indicates a decrease in the cell population at the given time point shown in the column header

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