Fig. 2

Anti-CD300e antibodies correlate with the improvement of insulin resistance in patients with obesity. a The presence of anti-CD300e antibodies in patients with obesity before weight loss inversely correlates with the amelioration of insulin resistance (expressed as % HOMA-IR improvement in AWL vs PWL) after bariatric surgery-induced weight loss. Non-parametric correlation was measured using the Spearman rank correlation coefficient (R = − 0.31; P = 0.02). b Receiver Operating Characteristic (ROC) curve analysis was used to determine the potential predictive role of serum anti-CD300e antibodies in the successful improvement of insulin sensitivity after bariatric surgery-induced weight loss (expressed as > 40% amelioration in HOMA-IR in AWL vs PWL). Cut-off > 0.64; Area under curve = 0.725; p = 0.047