Fig. 5
From: Serinc2 deficiency causes susceptibility to sepsis-associated acute lung injury
Serinc2 overexpression inhibits LPS-induced apoptosis in RAW264.7 cells. A Representative TUNEL staining images (left) and quantification data (right) showing the impact of Serinc2 overexpression on LPS-induced apoptosis in RAW264.7 cells. *P < 0.05, **P < 0.01 vs. Vector; ##P < 0.01 vs. PBS. n = 3. B Immunoblots showing the impact of Serinc2 overexpression on LPS-induced changes of cleaved caspase-3, Bax, and Bcl2. C Quantification of cleaved caspase-3, Bax and Bcl2 expression relative to GAPDH. *P < 0.05, **P < 0.01 vs. Vector; #P < 0.05, ##P < 0.01 vs. PBS. n = 3. D Immunoblots showing the impact of Serinc2 overexpression on LPS-induced Akt phosphorylation. E Quantification of Akt phosphorylation relative to its total protein. *P < 0.05, **P < 0.01 vs. Vector; ##P < 0.01, ###P < 0.001 vs. PBS. n = 3