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Fig. 4 | Journal of Inflammation

Fig. 4

From: USP10 alleviates sepsis-induced acute kidney injury by regulating Sirt6-mediated Nrf2/ARE signaling pathway

Fig. 4

USP10 reduces CLP-induced apoptosis in renal tissues. (A) Representative TUNEL staining images of renal tissues of the Sham + Ad-GFP, Sham + Ad-USP10, CLP + Ad-GFP and CLP + Ad-USP10 groups (n = 8) indicating the apoptotic rate, bar = 20 μm. (B) Western blot images demonstrating Bcl-2, Bax, and cleaved caspase-3 expression levels in renal tissues of the Sham + Ad-GFP, Sham + Ad-USP10, CLP + Ad-GFP and CLP + Ad-USP10 groups, **p < 0.01. GAPDH was used as an internal control

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