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Fig. 11 | Journal of Inflammation

Fig. 11

From: Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway

Fig. 11

RNA-sequencing (RNA-seq) data showing significantly downregulated pathways by esomeprazole in TGFβ (10 ng/mL) stimulated mouse lung fibroblasts. The data was analyzed for statistical significance and clustered using GO Enrichment Analysis of differentially expressed genes (DEGs). Several collagen-related genes (the number of genes are shown in brackets) are downregulated by esomeprazole, and the pathways are shown in boxes. *p < 0.05 compared to TGFβ only control. Experiment was run in duplicate for each condition

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Journal of Inflammation

ISSN: 1476-9255

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