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Fig. 10 | Journal of Inflammation

Fig. 10

From: Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway

Fig. 10

Gene networks that are activated in IPF lung fibroblasts were analyzed using ToppFun functional enrichment analysis and visualized using Cytoscape software platform. Orange colored circles represent genes that are upregulated in IPF lung fibroblasts and downregulated by esomeprazole while the purple-colored circles represent genes that are downregulated in IPF lung fibroblasts but upregulated by esomeprazole. The blue-colored squares represent enriched biological processes for the inversely correlated genes between control and esomeprazole treatment

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