Fig. 3
Comparison of PGE2 and PGF2α in mouse uteruses among each group. The mice were pretreated with saline, or estradiol (0.2 mg/ml) and oxytocin (2 U/ml) to build a PD model, or MCC950 (2 mg/ml, an NLRP3 inhibitor) in the presence of estradiol and oxytocin. a Levels of PGE2 and b levels of PGF2α were assayed by ELISA. The results are presented as means ± SD (n = 5). *P < 0.05, **P < 0.01 compared to the PD group