Fig. 3
From: Nrdp1 increases neuron apoptosis via downregulation of Bruce following intracerebral haemorrhage
Nrdp1 promotes Bax/Bcl-2 ratio and caspase-3 activity. Neuron was isolated from the cerebral cortex of newborn mice. Ad-Nrdp1 or control transduced neurons were subjected to erythrocyte lysis treatment for 24 h. a Bax/Bcl-2 levels of neurons were determined by western blot analysis. b Caspase-3 activity was determined by the ApoAlert caspase-3 colorimetric assay kit. Hydrolysed pNA was detected using a Multiscan MS colorimeter at 405 nm