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Table 3 Distribution of SNP variations among study participants - Recessive model

From: SNP variations in IL10, TNFα and TNFAIP3 genes in patients with dry eye syndrome and Sjogren’s syndrome

SNP

Risk Allele

Allele

SSa (n = 82) %

DESb (n = 98) %

P (χ2)

CEUc Freq. (HapMap)

TNFα (rs1800629)

G

     
  

G Allele

84.2

70.3

 

82.7

 

A Allele

15.8

29.7

 

17.3

    

0.56

 

IL10 (rs1800896)

A

     
  

G Allele

37.9

42.8

 

53.1

 

A Allele

62.1

57.2

 

46.9

    

0.23

 

TNFAIP3 (rs2230926)

G

     
  

T Allele

94.1

91.6

 

97.3

 

G Allele

5.9

8.4

 

2.7

    

0.54

 
  1. a - ss (Sjogren’s Syndrome); b − DES (Dry Eye Syndrome)
  2. c − CEU (C): Utah residents with Northern and Western European ancestry from the CEPH collection. Data is available at Hapmap
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Journal of Inflammation

ISSN: 1476-9255

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