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Fig. 1 | Journal of Inflammation

Fig. 1

From: Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus

Fig. 1

Levels of mRNA encoding NEK7, NLRP3 inflammasome components, and downstream cytokines in peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients and healthy controls, as examined by RT-PCR and statistically analyzed by the Mann-Whitney U test. SLE patients showed lower mRNA levels of NEK7 (a), NLRP3 (b), and ASC (c), but higher levels of Caspase-1 (d), IL-1b (e), and IL-18 (f)

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