Fig. 1From: Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosusLevels of mRNA encoding NEK7, NLRP3 inflammasome components, and downstream cytokines in peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients and healthy controls, as examined by RT-PCR and statistically analyzed by the Mann-Whitney U test. SLE patients showed lower mRNA levels of NEK7 (a), NLRP3 (b), and ASC (c), but higher levels of Caspase-1 (d), IL-1b (e), and IL-18 (f)Back to article page