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Fig. 2 | Journal of Inflammation

Fig. 2

From: Intestinally-restricted Janus Kinase inhibition: a potential approach to maximize the therapeutic index in inflammatory bowel disease therapy

Fig. 2

The effects of orally (PO) dosed tofacitinib (Tofa; 5–30 mg/kg TID) on (a) colon density, (b) weight (b), and (c) length following oxazolone (Oxa) challenge to sensitized mice. Data are expressed as mean ± SEM (n = 9–35). **** p < 0.0001 vs. Veh/Veh (Student’s t-test), ## p = 0.003 or 0.006, ### p = 0.0004, and #### p < 0.0001 vs. Veh/Oxa (One-way ANOVA, Fisher’s LSD post hoc test)

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Journal of Inflammation

ISSN: 1476-9255

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