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Table 4 Test characteristics based on optimal cut-off values for iron deficiency, determined by ROC curve analysis and comparison between AUCROC for MCH, Iron, TSAT and ferritin, respectively, and AUCROC for hepcidin

From: Evaluation of a competitive hepcidin ELISA assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients

Variable

Sensitivity (%)

Specificity (%)

ROC area

Cut-off

PV+ (%)

PV- (%)

p

MCH

56

89

0.78

28 pg

83

67

0.22

Iron

73

74

0.63

6.5 μmol/L

73

73

0.03

TSAT

70

74

0.74

14.5%

73

71

0.11

Ferritin

91

83

0.93

87 μg/L

84

90

0.58

Hepcidin

100

67

0.90

21 μg/L

75

100

–

  1. ROC receiver operating characteristics, MCH mean corpuscular haemoglobin, TSAT transferrin saturation, PV+ positive predictive value, PV negative predictive value
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Journal of Inflammation

ISSN: 1476-9255

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