Table 1 Effect of resveratrol (5, 10 and 20Â mg/kg) on different neurological scoring tests on 21st day
From: Resveratrol protects against ICV collagenase-induced neurobehavioral and biochemical deficits
Behavioral test | Horizontal Bar test | Cylinder Test | Spontaneous motility | Forelimb flexion | Righting reflex |
|---|---|---|---|---|---|
Group | |||||
Control | 4.0 ± 0.0 | 43.4 ± 6.9 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 |
Sham | 3.8 ± 0.4 | 42.8 ± 2.9 | 0.8 ± 0.2 | 1.0 ± 0.0 | 1.0 ± 0.0 |
Control +RSV (20 mg/kg) | 3.8 ± 0.4 | 41.6 ± 2.8 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 |
ICV-collagenase (1 IU) | 0.6 ± 0.4# | 10.3 ± 3.0# | 0.2 ± 0.2# | 0.2 ± 0.2# | 0.2 ± 0.0# |
ICH+ RSV (5 mg/kg) | 1.8 ± 0.4 | 23.8 ± 5.9 | 0.4 ± 0.2* | 0.6 ± 0.2 | 0.0 ± 0.0 |
ICH + RSV (10 mg/kg) | 2.8 ± 0.4* | 34.2 ± 5.2* | 0.8 ± 0.2* | 0.6 ± 0.2 | 0.2 ± 0.2 |
ICH + RSV(20 mg/kg) | 3.4 ± 0.4* | 38.4 ± 6.2* | 1.0 ± 0.0* | 1.0 ± 0.0* | 1.0 ± .00*,$ |