Table 1 Amniotic fluid concentration of mediators showing statistically significant difference in the three groups of examined patients

Down-regulated

IL-9***

35.69 (33.96–50.89)^a,d

5.89 (0.15–14.31)

7.52 (4.61–10.01)

TNF-α***

61.63 (56.49–72.93)^a,d

1.63 (1.63–30.97)

19.99 (1.63–29.06)

IP-10***

38964 (27318–108516)^a,d

7739 (4945–14536)

8732 (5422–12633)

IFN-γ***

66.84 (51.9–76.64)^a,d

24.7 (17.66–44.11)

27.7 (12.88–47.51)

MCP-3***

174.3 (89.8–216.3)^a,d

28.63 (22.13–44.32)

30.49 (23.79–41.70)

IL-15***

81.27 (0.42–99.4) ^a,e

0.42 (0.42–0.42)

0.42 (0.42–0.42)

IL-1α***

7.9 (0.35–11.75)^c,d

0.35 (0.35–0.35)

0.35 (0.35–0.35)

IL-2RA**

1659 (771,5–2414)^e

800.9 (426.2–3125)

5957 (496.2–854.5)

Il-12p40**

1809 (1170–2518)^e

1.17 (1.17–917)

1.17 (1.17–1.17)

IFN-α2**

195.1 (128.9–233.1)^c,e

127.3 (103.2–146.8)

120.1 (98.18–135)

IL-2*

30.04 (0.2–35.02)^c,f

0.2 (0.2–2.95)

0.2 (0.2–4.1)

IL-4*

1.97 (0.06–2.6)^c

0.06 (0.06–1.475)

1.09 (0.06–2.1)

EOTAXIN*

300.4 (11.49–432.1)^c,f

6.01 (0.48–23.2)

15.67 (0.48–31.28)

PDGF-BB*

89.13 (53.04–122.1)^c

39.86 (30.24–70.64)

50.43 (30.62–95.22)

RANTES*

37.75 (7.07–42.58)^c

0.52 (0.52–32.96)

21.37 (0.52–39.84)

Il-18*

240 (82.3–336.6)^f

98.97 (47.37–263.3)

67.72 (52.95–164.1)

MIF*

2155 (1587–3005)^c

1440 (1063–1804)

1446 (1098–2232)

Up-regulated

Il-17***

37.02 (32.75–45.11)^d

0.44 (0.44–205.5) ^g

302.8 (100–480.6)

FGF-b***

36.59 (34.57–39.21)^d

0.25 (0.25–105.8) ^g

100 (99–202.2)

G-CSF***

115.5 (45.26–354)^d

162 (43.92–599.8) ^h

742.1 (362–1943)

GM-CSF***

231 (201.8–253.8)^b

300 (284.2–325.8)

350.5 (300–411.4)

MCP-1*

167.8 (78.68–386–7)^f

401.2 (215.6–515.5)

374.6 (258.4–695.2)

IL-3*

404.7 (321.4–483.7)^c

537.7 (398.1–697)

537.7 (350.3–612.1)

SDF-1α*

152 (129.8–661.2)^f

541 (261.1–703.5)

617 (541.3–711.8)