Fig. 5

Low-dose poly I:C-induced increases in KC in BALF were suppressed by CIC plus IND, but not by either when administered independently. Effects of CIC and IND used independently and their combination on airway inflammation induced by poly I:C stimulation of mice. Mice were anesthetized and received poly I:C, 3 μg (a) or 30 μg (b) i.t., 4 h after the administration of CIC (3 μg) and/or IND (3 μg) i.t.. Twenty four hours after poly I:C administration, bronchoalveolar lavage fluid was collected and ELISA of KC, MIP-1β and IL-6 were performed. *p < 0.05 compared with stimulated control. Data is expressed as the means ± SEM of 6–12 mice