Table 4 Effect of metformin with different doses on blood biochemistry
From: Effects of metformin on blood and urine pro-inflammatory mediators in patients with type 2 diabetes
Variables | Metformin (1000 mg) | Metformin (1500 mg) | P value | ||
|---|---|---|---|---|---|
Mean ± SD | N | Mean ± SD | N | ||
Blood glucose (mmol/L) | 6.44 ± 0.96 | 91 | 6.27 ± 1.04 | 21 | 0.4684 |
Systolic blood pressure (mmHg) | 133.67 ± 11.16 | 91 | 131.67 ± 11.70 | 21 | 0.4640 |
Diastolic blood pressure (mmHg) | 73.10 ± 6.73 | 91 | 76.24 ± 8.81 | 21 | 0.0727 |
Hemoglobin A1c (%) | 6.36 ± 0.57 | 91 | 6.55 ± 0.58 | 21 | 0.1797 |
Body mass index | 25.64 ± 3.52 | 91 | 25.75 ± 4.23 | 21 | 0.8989 |
Total cholesterol (mmol/L) | 4.68 ± 1.36 | 91 | 4.85 ± 0.76 | 21 | 0.5970 |
Triglyceride (mmol/L) | 2.00 ± 1.38 | 91 | 1.48 ± 0.45 | 21 | 0.0940 |
HDL(mmol/L) | 1.13 ± 0.31 | 46 | 1.15 ± 0.30 | 13 | 0.7942 |
LDL (mmol/L) | 2.58 ± 0.83 | 91 | 3.03 ± 0.66 | 21 | 0.0212 |
VLDL (mmol/L) | 0.82 ± 0.42 | 46 | 0.75 ± 0.38 | 13 | 0.5954 |
Creatinine (μmol/L) | 82.07 ± 15.98 | 91 | 87.14 ± 22.93 | 21 | 0.2321 |