Table 1 Comparison of spike recovery of turbidimetric and chromogenic LAL assay

 HD patients (n = 5)

 Endotoxin content (EU/ml) of sample

0 [IQR 0–0.017]

0.026 [IQR 0–0.049]

0.074 [IQR 0.033–0.1]

0.242 [IQR 0.198–0.331]

1.69 [IQR 1.492–1.859]

-

 Spike recovery (%)

-

15.3 [IQR −7.3–97.6]

40.2 [IQR 32.8–100.4]

46.4 [IQR 39.6–63.8]

67.6 [IQR 59.7–73.7]

53.8 [IQR 34.0–78.9]

 Endotoxin content (EU/ml)

0.041 [IQR 0.016–0.081]

0.109 [IQR 0.092–0.118]

0.176 [IQR 0.126–0.205]

0.525 [IQR 0.408–0.817]

2.715 [IQR 2.2–3.108]

-

 Spike recovery (%)

-

125.3 [IQR 74.1–142.6]

129.9 [IQR 99.1–137]

96.7 [IQR 78.3–147.1]

108.6 [IQR 85.9–121.7]

113.8 [IQR 85.6–133.5]

P (for % spike recovery)

0.08

0.043^*

0.043^*

0.043^*

<0.001^*

 Healthy (n = 5)

 Endotoxin content (EU/ml)

0

0 [IQR 0–0.03]

0.031[IQR 0–0.04]

0.258 [IQR 0.109–0.267]

0.944 [IQR 0.636–1.434]

-

 Spike recovery (%)

-

0 [IQR 0–60.8]

31.5 [IQR 0–40.0]

51.5 [IQR 21.8–53.4]

37.7 [IQR 25.4–57.4]

34.0 [IQR 4.7–53.9]

 Endotoxin content (EU/ml)

0 [IQR 0–0.013]

0.071 [IQR 0.061–0.12]

0.151 [IQR 0.141–0.174]

0.532 [IQR 0.503–0.616]

2.132 [IQR 2.108–2.46]

-

 Spike recovery (%)

-

142.4 [IQR 95.1–212.5]

146.4 [IQR 127–173.4]

102.2 [IQR 99.9–123]

84.2 [IQR 82.6–101.3]

114.0 [IQR 98.3–145.4]

P (for % spike recovery)

0.043^*

0.043^*

0.043^*

0.043^*

<0.001^*