Fig. 1

The effects of Abn-CBD treatment on macroscopic damage score and MPO activity. TNBS-treated mice were given O-1918 (5 mg/kg) and/or Abn-CBD (5 mg/kg) twice daily for 3 days. Macroscopic damage score (a) and myeloperoxidase activity (b) were determined at the end of the experiment, 24 h after the last dose of drug. Abn-CBD significantly reduced macroscopic damage and MPO activity, and effect that was blocked by O-1918. Data were analyzed with one-way ANOVA with Tukey’s post-hoc test. *, p < 0.05 when compared to control and Abn-CBD + O-1918 (a and b) and when compared to O-1918 (b); n ≥ 10/group