Fig. 3From: AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood flow recovery in rats with critical limb ischemiaEPO reduces the infarcted area in ischemic quadriceps. The infarcted area of the quadriceps was determined using Hematoxylin and Eosin (H&E) staining. a Quadricep section from normal rats. b Quadricep section from rats with critical limb ischemia (CLI). c Quadricep section from CLI rats treated with EPO. d Quadricep section from CLI rats treated with AG490. e Quadricep section from CLI rats treated with EPO and AG490. f Quantitative evaluation of the infarct areas in quadriceps. Statistical analysis used one-way ANOVA followed by Bonferroni multiple comparison post hoc test (n = 8 for each group). Symbols (*, †, ‡, §) indicate significance at p value less than 0.05Back to article page