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Table 1 The serum TGF-β1 at different times (days) (ng/ml, \( \overline{x}+s \))

From: Effects of CpG Oligodeoxynucleotide 1826 on transforming growth factor-beta 1 and radiation-induced pulmonary fibrosis in mice

Group Mice(n) 1 d 5 d 15 d 30 d 90 d
Control 6 107.511 ± 10.032 103.027 ± 11.797 117.598 ± 16.270 108.595 ± 17.082 123.615 ± 17.491
RT 6 137.800 ± 9.694a 171.247 ± 13.449ac 203.633 ± 9.775ac 237.516 ± 11.589ac 174.161 ± 16.690ac
CpG
RT + CpG
6
8
116.985 ± 17.541
120.275 ± 21.534
122.065 ± 22.832
138.600 ± 7.388ab
105.213 ± 19.539
157.809 ± 12.353abc
112.231 ± 14.892
180.615 ± 13.091abc
102.731 ± 16.177
146.649 ± 12.004bc
  1. Notes: F = 4.959, P < 0.05 on days 1; F = 23.1, P < 0.05 on days 5; F = 51.743, P < 0.05 on days 15; F = 114.643, P < 0.05 on days 30; F = 30.874, P < 0.05 on days 90; a P < 0.05 versus control at t = 5.318, 9.432, 11.103, 15.298, 5.913, 6.260, 4.822 and 8.197; b P < 0.05 versus RT at t = 5.212, 7.126, 7.972 and 3.785; c P < 0.05 versus CpG at t = 4.546, 11.034, 16.263, 8.692, 5.573, 8.448 and 6.167
  2. Abbreviations: CpG cytosine-guanine, RT irradiation, n number, d days