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Fig. 4 | Journal of Inflammation

Fig. 4

From: The effect of high glucose on the inhibitory action of C21, a selective AT2R agonist, of LPS-stimulated tissue factor expression in human mononuclear cells

Fig. 4

Antagonism by PD123,319 (,10−6M), a selective AT2R blocker [26], of C21-mediated inhibition (♦) of LPS(100 ng/ml)-induced Tissue Factor procoagulant activity in normal (left panel, NG, 5.5 mM) and high (right panel, HG, 50 mM) glucose conditions. Mean ± SD, n = 6 experiments per group. ! p < 0.001 vs. vehicle; *p < 0.001 C21 (♦) vs C21+ PD123,319 ()

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