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Table 4 Differentially expressed cytokines in clodronate vs. no-clodronate conditions

From: Characterizing heterogeneity in the response of synovial mesenchymal progenitor cells to synovial macrophages in normal individuals and patients with osteoarthritis

Normal (N = 4)

OA (N = 8)

INFγ

TNFα

IL-4

IL-10

INFγ

TNFα

IL-4

IL-10

MCP-1

MCP-1

MCP-1

MCP-1

IL-10

Eotaxin

IL-15

TNF-β

p = 6.2x10-5

p = 3.1x10-5

p = 9.8x10-5

p = 6.7x10-6

p = 2.0x10-6

p = 4.2x10-8

p = 5,6x10-6

p = 4.6x10-5

    

VEGF

MIP-1α

Fit-3 L

EFG

p = 3.6x10-6

p = 3.6x10-5

p = 0.0002

p = 5.4x10-5

    

TGFα

MIP-1β

VEGF

MIP-1α

p = 9.0x10-6

p = 0.0008

p = 0.0005

p = 0.0002

    

GRO

  

IL-4

p = 2.0x10-5

p = 0.0003

    

RANTES

  

IL-7

p = 4.4x10-5

p = 0.0005

    

Eotaxin

  

IL-12p40

p = 8.2x10-5

p = 0.0005

    

MCP-3

  

MCP-3

p = 8.6x10-5

p = 0.0009

    

IL-5

   

p = 0.0001

    

EGF

   

p = 0.0002

  1. After Bonferroni correction p < 0.05/41 = 0.0012