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Fig. 6 | Journal of Inflammation

Fig. 6

From: The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets

Fig. 6

Cell morphologic changes of RA synovial fibroblasts after 48 h incubation with WIN (0 μM, 1 μM, 10 μM). Arrows indicate vacuolization; the black rimmed cell is an example of sharp edged cell bodies in contrast to unstimulated control fibroblasts. Regenerated = WIN wash-off after 48 h and supplementation with fresh medium containing 10 % FCS without WIN

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Journal of Inflammation

ISSN: 1476-9255

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