Table 1 Patients characteristics
Variable | NSCLC | Healthy subjects |
|---|---|---|
n = 80 | n = 16 | |
Gender n (%): | ||
Female | 16 (20) | 3 (18.8) |
Male | 64 (80) | 13 (81.2) |
Age, years, median (range) | 66 (45–77) | 34 (19–77)** |
Smoking history n (%)* | ||
Non- smokers | 14 (17.5) | 10 (62.5) |
Smokers | 66 (82.5) | 6 (37.5) |
Smoking pack-years, median (range) | 30 (0–60) | 2,5 (0–50)** |
FEV1 % of pred. median (range) | 83 (33–144) | 93 (70–114) |
FEV1/FVC ratio % of pred., median (range) | 89 (49–123) | 107 (86–114) |
Histological NSCLC type: | ||
Adenocarcinoma | 38 (47.5) | _ |
Squamous cell carcinoma | 36 (45) | |
Large cell carcinoma | 5 (6.2) | |
Adenosquamous carcinoma | 1 (1.2) | |
NSCLC stage: | ||
Stage IA | 4 (5.0) | _ |
Stage IB | 19 (23.8) | |
Stage IIA | 21 (26.2) | |
Stage IIB | 5 (6.2) | |
Stage IIIA | 28 (35.0) | |
Stage IIIB | 3 (3.8) | |
T status: | ||
T1a | 2 (2.5) | _ |
T1b | 11 (13.8) | |
T2a | 37 (46.2) | |
T2b | 8 (10.0) | |
T3 | 18 (22.5) | |
T4 | 2 (5.0) | |
N status | _ | |
N0 | 35 (43.8) | |
N1 | 26 (32.5) | |
N2 | 17 (21.2) | |
N3 | 2 (2.5) | |
Diferenciation: | _ | |
Poor | 46 (57.5) | |
Other | 33 (41.2) |