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Figure 4 | Journal of Inflammation

Figure 4

From: Pentoxifylline reduces the inflammatory process in diabetic rats: relationship with decreases of pro-inflammatory cytokines and inducible nitric oxide synthase

Figure 4

Pentoxifylline (PTX, 50 and 100 mg/kg) treatments of diabetic rats for 5 days significantly decrease TNF-alpha levels in rat paws, at both doses, as related to untreated-diabetic animals and to normal controls (non-diabetic rats). Measurements were done in homogenates and the values are means ± SD from groups of three animals each. Glibenclamide (GLI, 5 mg/kg) was used as reference. a. vs. normal controls, q = 26.65; b. vs. normal controls, q = 6.476; c. vs. untreated-diabetic group, q = 20.18; d. vs. untreated-diabetic group, q = 29.09; e. vs. normal controls, q = 20.46; f. vs. untreated-diabetic group, q = 6.194 (One-way ANOVA and Tukey’s as the post hoc test).

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Journal of Inflammation

ISSN: 1476-9255

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