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Table 2 Differences in peripheral blood and muscle gene expression levels of adipokines between adult dermatomyositis patients and non-disease adult controls*

From: Adipokine gene expression in peripheral blood of adult and juvenile dermatomyositis patients and their relation to clinical parameters and disease activity measures

 

Peripheral blood

 

Muscle

 
 

Adult DM

Non-disease adult controls

P Value

Adult DM

Non-disease adult controls

P Value

 

(N = 21)

(N = 5)

 

(N = 5)

(N = 5)

 

Leptin

0.7 (0.6, 0.8)

0.8 (0.7, 0.8)

0.49

1.5 (0.9, 2.5)

1.4 (0.5, 1.9)

0.60

Adiponectin

0.1 (0.1, 12.1)

0.2 (0.0, 12.4)

0.63

1.7 (0.9, 4.6)

1.3 (0.8, 2.0)

0.60

Resistin

1.4 (0.9, 2.8)

0.6 (0.5, 2.5)

0.18

23.2 (7.7, 40.4)

2.6 (2.5, 7.4)

0.047

Visfatin

1.9 (1.7, 2.5)

0.3 (0.2, 1.1)

0.004

1.9 (1.8, 2.7)

1.0 (1.0, 1.1)

0.08

IL-6

0.4 (0.3, 0.7)

1.4 (0.7, 1.6)

0.06

2.9 (1.7, 4.0)

1.0 (0.8, 1.1)

0.047

TNF-α

0.7 (0.5, 0.8)

0.8 (0.7, 1.5)

0.28

1.8 (1.1, 2.4)

1.0 (0.9, 1.2)

0.25

  1. *Values are presented as median (25th percentile, 75th percentile). Gene expression levels of adipokines were normalized to the mean of age-matched controls. P-value is from Wilcoxon rank sum test.