Table 3 Results of uni- and multivariate Cox regressions for each biomarker restricted to time ≤ 5 years

HR (CI 95%)

P

HR (CI 95%)

P

Calprotectin

1.002 (1.000 – 1.004)

0.031

1.002 (1.000 – 1.004)

0.016

Neutrophil count

1.039 (0.978 – 1.103)

0.213

1.035 (0.971 – 1.103)

0.296

Lymphocyte count

0.604 (0.475 – 0.768)

<0.01

0.667 (0.522 – 0.851)

<0.01

NLR

1.104 (1.051 – 1.159)

<0.01

1.090 (1.036 – 1.148)

<0.01

YKL-40

1.001 (0.999 – 1.002)

0.318

1.001 (1.000 – 1.003)

0.086

Glucocorticoid use

HR (CI 95%)

P

Calprotectin

1.001 (0.998 – 1.003)

0.559

Neutrophil count

1.035 (0.945 – 1.133)

0.462

Lymphocyte count

0.946 (0.580 – 1.545)

0.825

NLR

1.010 (0.966 – 1.056)

0.665

YKL-40

1.006 (1.003 – 1.008)

<0.01