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Figure 3 | Journal of Inflammation

Figure 3

From: Crude extract of hydatid laminated layer from Echinococcus granulosus cyst attenuates mucosal intestinal damage and inflammatory responses in Dextran Sulfate Sodium induced colitis in mice

Figure 3

Pretreatment with hydatid LL protects BALB/c mice from DSS-induced colitis. A and B, On day 7, the colon of each mouse was removed and the length was measured; B, Representative photomicrographs of colons are shown. C, The colon of each mouse was weighed and the weight indicated is for 1 cm length of the colon. D, Histological scores for colon cellular infiltration and tissue alterations. All results are expressed as the mean ± standard error of mean. p values from LSD post-hoc ANOVA test are indicated (**p < 0.01, ***p < 0.001, ****p < 0.0001). The results are shown for 6 to 10 mice per group. E, Representative photomicrographs (×20, ×40) of H & E stained colon tissue from each group; (a, b) CTRL group, (c, d) DSS group, (e, f) LL + DSS group. M: Mucosa, SM: Submucosa. Red arrow: eroded mucosa, dark arrow: cell infiltrate extending throughout the mucosa and the submucosa, yellow arrow: epithelium intact, star: crypt destruction.

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