Figure 5

Influence of labda-8(17),12 E ,14-triene-2R,18-diol on cytokine production in PBMCs as quantitated by CBA analysis and flow cytometry. Cells were treated with a non-toxic concentration of 50 μM. Concentrations obtained of tested cytokines were log transformed in order to make the data comparable. Control treatments are unshaded whereas compound treated cells are shaded. IL-6 was the only cytokine that was up-regulated by the compound. The rest of the cytokines were significantly (*p < 0.05) down-regulated.