Low-dose aspirin decreases levels of TxB
and 12-HETE. Concentrations of (A) TxB2 and (B) 12-HETE were reduced in collagen-activated platelets following 75 mg aspirin oral administration to healthy volunteers (n = 19). (C) 12-HETE:TxB2 molar ratio is elevated following aspirin-treatment. Data are expressed as mean ± SEM.. ****P < 0.0001 and ***P < 0.0005.