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Table 1 Contrasts of ANCOVA at 6 hours post-dose after ex vivo LPS challenge

From: Characterization of inflammation and immune cell modulation induced by low-dose LPS administration to healthy volunteers

  0.5 ng/kg vs placebo 1 ng/kg vs placebo 2 ng/kg vs placebo
Estimated difference(%) p-value Estimated difference(%) p-value Estimated difference(%) p-value
TNF-α -13.6 0.6256 -66.4 0.0005 -74.7 <0.0001
IL-1β -30.0 0.1606 -65.8 <0.0001 -84.7 <0.0001
IL-6 34.8 0.0754 -31.3 0.0283 -41.3 0.0024
IL-8 55.1 0.0879 19.2 0.4961 -4.8 0.8475